Coleus Forskohlii Extract Forskolin 10%, 20% 98%
Active ingredients: forskolin
Specification: 10%, 20%
Appearance: Brown Yellow Powder
Used Part: Root
Test Method: TLC
Grade: Pharmaceuticals Ingredients
MOQ: 1kg
Brand Name: LeSen
Coleus Forskohlii Herb Extract Powder is drived from roots from Coleus Forskohlii. Coleus is used in India folk medicines and is a traditional digestive remedy. Currently the plant is extensively cultivated is Southern India. Forskohlii helps to lower blood pressure, dilates the blood vessels. It is concerted to be a good Heart tonic.
This "powder" herb has an active ingredient in it called forskolin. It has been used in ayruvedic medicine for many years. Forskolin's basic mechanism of action is that it increases the amount of cyclic AMP (adenosine monophosphate) in cells by activating an enzyme called adenylate cyclase. Cyclic AMP (cAMP) is one of the most important secondary messengers in the cell. It is considered to be one of the most important cell regulating compounds.
Function
1. Coleus Forskohlii Extract forskolin used as a medical herb extract to treat heart and lung diseases, intestinal spasms, insomnia, and convulsions;
2. It can activate the enzyme adenylate cyclase,responsible for executing a number of important hormonal processes;
3. It supposedly leads to blood vessel dilation, inhibition of allergic reactions, and possibly an increased secretion of thyroid hormone;
4. Coleus Forskohlii Extract with inhibition of the pro-inflammatory substance known as platelet-activating factor (PAF) 6 and inhibition of the spread of cancer cells.
Forskolin Chemical Properties |
Melting point | 282-232 °C |
alpha | D25 -26.19° (c = 1.68 in CHCl3) |
Boiling point | 520℃ |
density | 1.23 |
refractive index | 1.5300 (estimate) |
Fp | 172℃ |
storage temp. | room temp |
solubility | DMSO: 5 mg/mL stable at least 6 months at room temperature |
pka | 11.00±0.70(Predicted) |
form | powder |
color | off-white |
Water Solubility | Soluble in ethanol, dimethylsulfoxide and chloroform. Insolule in water. |
λmax | 305nm(lit.) |
Merck | 14,2476 |
BRN | 1692716 |
Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 4 months. |
InChIKey | OHCQJHSOBUTRHG-KGGHGJDLSA-N |
LogP | 2.406 (est) |
CAS DataBase Reference | 66575-29-9 |
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