2-Bromo-1-phenyl-pentan-1-one, molecular formula C11H13BrO, CAS 49851-31-2, molecular weight 241.124, is an organic compound. It appears as a transparent and colorless oily liquid at room temperature, with certain viscosity and fluidity. It has high purity and usually appears bright yellow. It appears as a transparent and colorless oily liquid at room temperature, with certain viscosity and fluidity. It has high purity and usually appears bright yellow. Its main use is as an intermediate in organic synthesis and pharmaceutical chemistry, especially in scientific research and the synthesis of drug molecules. This compound can be obtained by using benzophenone as the raw material and brominating it with sodium bromide. Its specific applications include the preparation of histone demethylase inhibitors, demonstrating its important role in the field of pharmaceutical chemistry. It can be used to prepare substituted imidazole derivatives with the following structures, which have efficient KDM1A enzyme inhibitory activity and selectivity beyond monoamine oxidase (MAO), and can be used for the prevention or treatment of diseases and conditions related to histone demethylase activity.

2-Bromo-1-phenyl-pentan-1-one, as an organic synthesis intermediate, has shown extensive application value in various fields such as chemistry, medicine, and scientific research. Its unique chemical structure and properties make it a key raw material for preparing various important compounds and drugs.

1. Organic synthesis intermediates

(1) Preparation of substituted imidazole derivatives: Through specific chemical reactions, it can be used to prepare substituted imidazole derivatives with efficient KDM1A enzyme inhibitory activity and selectivity beyond monoamine oxidase (MAO). These derivatives have potential application value in the pharmaceutical field.

(2) Other organic synthesis: Due to its unique chemical structure, it can be used as a key raw material in organic synthesis to synthesize compounds with specific structures and functions.

2. Pharmaceutical intermediates

(1) Preparation of histone demethylase inhibitors: There are literature reports that it can be used to prepare histone demethylase inhibitors. Histone demethylase plays an important role in cell biology, and its inhibitors can be used to treat diseases and conditions related to histone demethylase activity. These inhibitors have potential applications in the treatment of diseases and conditions related to histone demethylase activity. Therefore, the application prospects in the field of medicine are very broad.

(2) Drug molecule synthesis: It can also be used to prepare substituted imidazole derivatives with efficient KDM1A enzyme inhibitory activity and selectivity beyond monoamine oxidase (MAO). It can be used as a synthetic raw material for other drug molecules, for synthesizing drugs with specific pharmacological and biological activities. These compounds have potential application value in the pharmaceutical field, and can be used to prevent or treat diseases and conditions related to histone demethylase activity.