What is 20 Hydroxyecdysone?

20 Hydroxyecdysone also named Ecdysterone, is the main active ingredient of cyanotis arachnoidea extract, it is light yellow to white crystal powder different from the purity.

20-Hydroxyecdysone powder significantly increased by amino acids, protein chains to assemble into stimulating muscle cells in the cytoplasm of protein synthesis, and the ability to grow into proteins and migration process. It not only are beneficial to the health, which helps to stability in the safety of cortisol damage cell, make energy synthesis (ATP and muscle normalization procedure and improve liver function and peptide) quickly adapt to the organic physical environment and pressure changes. Ecdysterone is used to improve work ability, immune function, weight loss and low fat aspects have been reported problems.

What is the Function of 20 Hydroxyecdysone?

1. Use as supplement

20 Hydroxyecdysone and other ecdysteroids are marketed as ingredients in nutritional supplements for various sports, particularly bodybuilding. Evidence to support such use, however, is limited. A comprehensive study, designed to find any strength or athletic improvement from it, was published in 2006. The study looked for improvement in actual exercises performed and tested for improvements/increases in chemical indicators such as body composition.

The results of the 2006 study concluded that using 30 mg per day of it administered orally did not significantly affect anabolic or catabolic responses to resistance training, body composition, or training adaptations.

2. Use as research tool

This product and other ecdysteroids are used in biochemistry research as inducers in transgenic animals, whereby a new gene is introduced into an animal so that its expression is under the control of an introduced ecdysone receptor. Adding or removing ecdysteroids from the animal's diet then gives a convenient way to turn the inserted gene on or off (see ecdysone receptor). At usual doses, it appears to have little or no effect on animals that do not have extra genes inserted; it also has high bioavailability when taken orally, so it is useful for determining whether the transgene has been taken up effectively. For uses in gene therapy, it may be necessary to investigate more thoroughly the natural sources of ecdysteroids in humans (which appear to include dietary phytoecdysteroids, gut flora, helminth infections, and other diseases).

There is some in vitro evidence to show that Beta Ecdysterone has effects on some kinds of blood cells such as lymphocytes and neutrophils, and may act as an immunomodulator. This would explain the mechanism behind Helminthic therapy due to the production of ecdysteroids by helminths, as mentioned above.