Plant source: Saxifragaceae plant Bergenia purpurascens whole grass, thick leaf rock cabbage (B.crassifoloa, Astilbe macroflora) purple golden bovine plant Argentia crispa (Ardisia crispa) roots, stems, leaves. Bergenin powder is white loose needle-shaped crystal or crystalline powder; odorless, bitter taste; faded in light or heat. Dissolved in methanol, slightly soluble in water or ethanol.

Pharmacological effects

Bergenin powder has analgesic, sedative, hypnotic and calming effects. Its analgesic effect is weaker than pethidine and stronger than general antipyretic analgesics. There is no respiratory depression at therapeutic doses, nor does it cause gastrointestinal smooth muscle spasm. It has a good effect on chronic persistent pain and visceral dull pain, but has a poor effect on acute sharp pain (such as postoperative pain, traumatic pain, etc.) and advanced cancer pain. While producing analgesic effects, it can cause sedation and hypnosis. The mechanism of action of this product has yet to be elucidated, which may be related to the inhibition of the function of the dopamine receptor in the brain by inhibiting the upward activation of the brainstem network structure. The amount of treatment is not addictive.

1. Cough

2. The effect on the respiration of trachea and lung tissue: acting on the enzyme system containing thiol-containing essential groups can reduce tissue respiration, but the effect is not strong.

3. Anti-inflammatory; clinically mainly used to treat chronic tracheitis and chronic gastritis. It is also effective for stomach and duodenal ulcers.

Applications

1. Bergenin powder can be applied in pharmaceutical field, bergenin relieve cough and remove the phlegm. For Chronic Bronchitis use.

2. Bergenia purpurascens extract can be applied in cosmetics industry, bergenin can be used for skin whitening by inhibiting the activity of Tyrosinase.

3. It can be Applied as health care products, bergenin can supply nutrition and strengthen the body, also can help to stop bleeding and relieving cough.

4. It can be used as herbal antitussive expectorant. Bergenin has the function of curing for respiratory illness, such as chronic bronchitis,emphysema, pulmonary heart disease, bronchial asthma.