What is Nobiletin Powder?

Nobiletin powder is a citrus flavonoid. It has the typical flavonoid structure and contains 6 methoxyl groups, one more than tangeretin. This high level of methoxylation increases the hydrophobic character of tangeretin. Pure nobiletin has the appearance of colorless needles and has a bitter taste. Nobiletin seems to be a very noble phytochemical with many potential health benefits. The most studied properties of nobiletin are its anti-inflammatory and anti-cancer activities. Nobiletin also helps to lower cholesterol levels and some studies indicate that it may improve impaired memory loss and treat acne.  

Nobiletin powder acts directly as an antioxidant but also interferes with biological inflammatory processes. It inhibits the expression of genes involved in inflammation by blocking the binding of NF-kappaB with DNA. One study showed that nobiletin reduced airway inflammation of asthmatic rats. Treatment of skin cells with nobiletin also reduced inflammation caused by ultraviolet-B radiation.

COA

Functions of Nobiletin Powder

1. Antioxidant, anti-inflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol-lowering actions.

2. Inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG-CoA reductase and cyclooxygenase.

3. Improve the health of capillaries by reducing the capillary permeability.

4. Reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. The possible anti-cancer activity of hesperidin could be explained by the inhibition of polyamine synthesis.

Applications of Nobiletin powder

1. As Healthy Products ingredients.

2. As Nutrition Supplements ingredients.

3. As Pharmaceutical Industry & General Drugs ingredients.

4. As a health food and cosmetic ingredients.