What is papain?

Papain powder immature fruit contains papain, papa chymotrypsin A, papa chymotrypsin B, papaya peptidase B and other proteolytic enzymes. And the primary structure of four cysteine proteases is known to have a high degree of homology. Among them, papain is a thiol protease, which can hydrolyze the carboxyl ends of arginine and lysine in proteins and peptides, and can preferentially hydrolyze those peptides with two carboxyl groups or aromatic L-amino acids at the N-terminus of the peptide bond key.

Papain is a proteolytic enzyme with a molecular weight of 23406, consisting of a single peptide chain and containing 212 amino acid residues. At least three amino acid residues exist in the active center of the enzyme. They are Cys25, His159, and Asp158. When Cys25 is oxidized by an oxidant or bound to metal ions, the activity of the enzyme is inhibited, and the reducing agent cysteine (or Sulfite) or EDTA can restore enzyme activity. The other six cysteine residues form three pairs of disulfide bonds, none of which are in the active site.

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Benefits of Papain Powder

1. It is a useful digestive enzyme that can help the stomach to better decompose proteins and promote nutrient absorption. For example, it is very helpful for people with indigestion.

2. It has the function of dissolving fat and softening the skin. In addition, it also helps to remove dead cells and keep the skin healthy. This is why this enzyme is widely used in beauty products.

3. Papain powder has anti-inflammatory effects, soothes the stomach and intestines and reduces edema. The anti-inflammatory properties of papain can also treat burns and cold sores.

4. It can alleviate different food allergies, especially for the problems caused by indigestion of food protein.

5. The amino acids in papain can help relieve the symptoms of irritable bowel syndrome by preventing gastric acid reflux.

6. As a proteolytic enzyme, papain can also help cope with intestinal parasites. In addition, it has the function of decomposing food protein.

Uses of papain powder

1. Pharmaceutical industry applications: Papain powder-containing drugs can play anti-cancer, tumor, lymphocytic leukemia, protozoa and parasites, tuberculosis bacillus, etc., can anti-inflammatory, choleretic, analgesic, and aid digestion. Treatment of gynecological diseases, glaucoma, bone hyperplasia, gun knife wound healing, blood type identification, insect bites, etc.

2. Application in the food industry: Enzymatic reactions can be used to hydrolyze food macromolecule proteins into small molecule peptides or amino acids. It is used to hydrolyze animal and vegetable proteins, make tender meat powder, hydrolyze sheep placenta, hydrolyze soybeans, biscuit softener, noodle stabilizer, beer beverage clarifier, high-grade oral liquid, health food, soy sauce brewing and wine fermentation agent. The use of effectively transformed protein greatly improves the nutritional value of food and reduces costs. Conducive to digestion and absorption of the human body.

3. Application of beauty cosmetics.

4. Industrial application of daily chemicals.

5. Feed industry application.