What is TUDCA Powder Bulk?

Tauroursodeoxycholic acid (TUDCA) is an endogenous hydrophilic tertiary bile acid that can be produced at low levels in the human body. Under ER stress conditions, TUDCA's treatment of MSC (Mesenchymal Stem Cells) reduces the activation of ER stress-related proteins, resulting in a reduction in endoplasmic reticulum stress-mediated cell death. TUDCA treatment increases the expression of PrPC (cellular prion protein). TUDCA regulates the differentiation of stem cells into various lineages, such as adipogenic and osteogenic lineages. TUDCA relieves endoplasmic reticulum stress, prevents unfolded protein response dysfunction, and stabilizes mitochondria. Under ER stress, compared with untreated cells, TUDCA treatment significantly increased the expression of BCL-2, and significantly reduced the expression of Bax, cleaved caspase-3 and cleaved PARP-1.

What is the role of TUDCA Powder Bulk in the body?

Like many compounds in your body, TUDCA is made through a microbial process.

First, bile salts are released into your intestines through the liver and bile ducts. Microbes in the large intestine then metabolize bile salts into ursodeoxycholic acid (UDCA). Next, it combines with taurine molecules to produce TUDCA. This entire process occurs naturally in your body and is supported when you have a healthy amount of bile salts.

A healthy person produces a very small amount of TUDCA and recovers approximately 95% of bile salts through the enterohepatic circulation-when bile is absorbed through the intestines and returned to the liver through the hepatic portal vein.