What is Astragalus Root Extract?

Astragalus Propinquus is a flowering plant belonging to Fabaceae.

Astragalus Membranaceus is one of the 50 basic herbs used in traditional Chinese Medicine (TCM) with more than a thousand years of history.

We use it to reinforce Qi, strengthen the superficial resistance, promote the discharge of pus, and help the growth of new tissue.

Astragalus Membranaceus Applications

Most ingredient suppliers make the root of Astragalus Membranaceus into powder and liquid extracts.

Some people use astragalus as a general tonic to protect the liver and fight bacteria and viruses. It is also used to reduce the side effects associated with cancer treatment.
Doctors sometimes inject Astragalus Propinquus into the vein to fight the side effects of cancer treatment, heart failure, diabetes, and lupus (systemic lupus erythematosus).

You can also apply astragalus to the skin to increase blood flow to the area and speed wound healing.

Many health brands supply astragalus root extract capsules in combination with other herbs.

Astragalus Propinquus Specifications

Astragalus Mongholicus include triterpenoids (such as astragalosides),

Isoflavones(including kumatakenin, calycosin, and formononetin),

polysaccharides, glycosides, and malonates.

Astragaloside IV Powder

Product Name	Astragaloside IV
Other Name	Astrasieversianin XIV
CAS Number	84687-43-4
Molecular Formula	C41H68O14
Molecular Weight	784.97
Appearance	Brown yellow powder (0.3%,1%,5%,10%,20%,50%), Light yellow powder(70%,90%),White powder (98%)
Mechanism	Telomerase Activator
Chemical structure

More and more people in different countries use Astragaloside IV capsules as a safe dietary supplement although FDA and GRAS haven’t reorganized it.

Astragaloside IV is a saponin extracted from the root of Astragalus Membranaceus.

You may know the lowest specification of astragaloside IV(CAS number 84687-43-4)is 0.3%, the highest spec is 98%, and the pervasive item is astragaloside IV at 95%. However, if you need other content, you can get them from IdoBio .

How does Astragaloside IV (CAS NO.84687-43-4) work?

Astragaloside IV has supper power in protecting telomeres integrity and remitting toxins that cell damage caused.

As you know, the telomere is the protective structure at the end of each chromosome. It is directly associated with youth. As we age, the area of the chromosome (telomere) becomes shorter over time. The shortening will lead to impaired cellular and disordered tissue function.

The cell produces new cellular by replicating DNA.

Once DNA splits to produce its copy, this process will cause a little damage to the genetic material, and these DNA strands will eventually be separated, resulting in many dysfunctional cells.

Telomeres cover the ends of the DNA strand to help the DNA strand lock well. But over time, telomeres will be shortened by DNA replication and oxidative damage. When most telomeres are too short to finish DNA replication, it will cause significant damage to surrounding tissues. Then aging and disease will attack us.

Clinical researches indicate that Astragaloside IV powder can lengthen the telomeres.

Cycloastragenol Powder

Product Name	Cycloastragenol
Other Name	Cyclogalegigenin, Astramembrangenin
CAS Number	78574-94-4, 84605-18-5
Molecular Formula	C30H50O5
Molecular Weight	490.72
Appearance	Brown yellow powder (5%, 10%), Light yellow powder (50%, 90%), White powder (98%)
Mechanism	Telomerase Activator
Chemical structure

What is Cycloastragenol(CAG)?

Cycloastragenol (CAG) is the hydrolysate of Astragaloside IV. Their benefits are very similar.

TA s launched Cycloastragenol as a medical food (GRAS recognized as safe ) in the name of TA-65 in 2007 in the US.TA 65 or TA65 has been the most common name for Cycloastragenol based on those many years of market promotion.

Cycloastragenol application

Have you used any astragalus extract before?

Lots of brands use Cycloastragenol powder is in a relatively new anti-aging dietary supplement, cosmetics formulas, and luxury skincare due to its antioxidant.

Cycloastragenol method of action

Nobel Prize winners in 2009 covered telomeres and telomerase mechanisms to safeguard chromosomes relating to human aging and health. Alzheimer’s, brittle bones, and cancer may appear if telomeres keep shortening.

You’ll get a telomeres booster if you’re using this astragalus supplement.

Hundreds of researchers reported that Cycloastragenol could help maintain the length of telomeres. It has multiple benefits for the body’s health, such as promoting the immune system, cell longevity, overall health, etc.

Some scientists believe Cycloastragenol（CAS#84605-18-5）can enable a longer human lifespan.

You may find the mechanism of Cycloastragenol is almost the same as Astragaloside IV since they both effect as a telomerase activator.

Manufacturing Flow Chart of Cycloastragenol

We buy the dried Astragalus Root from the supplier, then inspect them to get a high quantity of raw material for cycloastragenol.

Later we smash the root into powder via machine,  Water Extraction,   Resin Adsorption, Resin Adsorption, Rinse With Ethanol, Membrane filtration, and Enrichment, then we get Astragaloside IV, Hydrolysis it, Crystallize to reach Cycloastragenol.

Cycloastragenol VS Astragaloside IV

Cycloastragenol and astragaloside IV are both from the extract of Astragalus Membranaceus.
We obtain Cycloastragenol by hydrolysis of astragaloside IV.

Both astragaloside IV and Cycloastragenol are telomerase activators with similar functions and benefits.

They have a similar structure, but Cycloastragenol has a lower molecular weight and higher bioavailability.

Therefore, the price of Cycloastragenol 98% powder is five times higher than Astragaloside IV 98% powder.

Besides, the effect of Cycloastragenol 98% appears to be potent ten times more than Astragaloside IV 98%.

The effect of 50 mg Astragaloside IV 9 equals 5 mg Cycloastragenol.

In conclusion, Cycloastragenol is an upgraded version of astragaloside IV with more bioactivity and higher cost.

Calycosin-7-O-beta-D-glucoside Powder

Product Name	Calycosin-7-O-beta-D-glucoside
Other Name	fCalycosin-7-O-β-D-glucoside; Calycosin 7-glucoside, 4-hydroxy-3-Methoxyisoflavone-7-sug, 3′-hydroxy-4′-methoxy isoflavone 7-sug
CAS Number	20633-67-4
Molecular Formula	C22H22O10
Molecular Weight	446.408
Appearance	Brown yellow powder
Chemical structure

Astragalus Propinquus extract benefits

• Hold back aging and increase life expectancy
• Support Cardiovascular Health
• Boost Immune and maintain healthy immunity
• Improve Inflammatory Response
• Increase your energy level.
• Better sleep quality.

Recommended dosage

You’ll get the double effect if you take astragaloside IV alongside Cycloastragenol.

• Astragaloside IV, 50-100mg per day
• Cycloastragenol, 10mg to 50mg per day
• Astragalus Root Extract, 250mg to 1000mg per day.

Caution

You’d better not intake astragalus Membranaceus if you’re pregnant, nursing women, children, or those with severe liver or kidney disease.

FAQ:

IdoBio Astragalus membranaceus descriptions

• Premium Extract
• Non-GMO Project Verified
• Gluten-Free
• 100% natural extract of astragalus