The main active ingredient of Cnidium Monnieri extract is osthole, also known as king's wort, which is extracted from the dried fruit of Cnidium Monnieri also called Fructus Cnidii. The in vitro test shows that Osthole can inhibit the activity of ringworm and mycobacteria, which can treat skin eczema and other diseases. The moisture absorption test of Osthole shows that it has good moisture absorption and moisturizing properties, which can be used in skin care products to prevent dry skin; and it can keep the skin clean, which has a good care effect on the skin. Osthole has antibacterial and anti-inflammatory effects, which can be used in the cosmetics industry for female toiletries, and its application in the cosmetics field is widely sought after.


 

Latin Name	Cnidium monnieri (L.)Cuss.
Active Ingredient	Osthole
Part Used	Fruit
Specification	10%-98%
CAS No.	484-12-8
Molecular Formula	C15H16O3
Molecular Weight	244.286

 

Why IdoBio Cube's Cnidium Monnieri Extract?

Cnidium Monnieri Extract Osthole 10% with the liquid state is one of our special specifications. This product specification can be said to be customized specifically for customers in the direction of pesticides, and the liquid form is more conducive to customers adding to the formula. In addition, the purity of our products is 10%, and different purity can be customized according to the different requirements of customers. In addition, during the transportation process, we can also match the relevant certification documents. Why not choose Cnidium Monnieri Extract Osthole 10%?
 

Application

1.As Pesticides & Bactericide

Fructus Cnidii Extract as a Phytogenous Pesticides and insecticide not only has insecticidal activity but also has bactericidal activity with broad-spectrum. the active ingredient "Osthole" in Fructus Cnidii Extract has contact with killing aphids and cabbage worms of cruciferous plants, meanwhile have good inhibition on Botrytis cinerea, Phyllosticta, Phomopsis asparagi, etc. also as can be appliable in keeping fruit and vegetable fresh.

2. Anti-pruritic

The antipruritic mechanism of extracts from Cnidium Monnieri is related to the stabilization of the mast cell membrane and inhibition of histamine release from skin mast cells, which has an obvious antipruritic effect. Experiments have shown that the active ingredient R2 of Cnidium Monnieri can significantly increase the itch-causing threshold of histamine phosphate in guinea pigs, significantly inhibit the itchy skin reaction induced by 4-aminopyridine in mice, inhibit the release of histamine from mast cells in skin tissues, and significantly counteract the swelling of the auricle in mice caused by xylene. The combination of serpentine and other coumarins blocked the signal transduction pathway caused by substance P and replaced the itch awareness to achieve the anti-itch effect.

3. Anti-inflammatory effect

In vitro experiments in mice showed that Cnidium Monnieri and Cnidium Monnieri is could inhibit the swelling of mouse ear shell caused by xylene and the increase of capillary permeability in mouse abdominal cavity caused by acetic acid, and significantly inhibit granuloma in mice. The anti-inflammatory effect of C. serrulata was achieved by inhibiting intracellular calcium flow and increasing the level of cyclic guanosine monophosphate, which affected the content of PG, NO, and MDA, and the activity of nitric oxide synthase. It has also been reported abroad that it affects the central nervous system by inhibiting peripheral inflammatory substances and achieves anti-inflammatory effects.

4. Antibacterial effect

The antimicrobial effect of Cnidium Monnieri on the clinical isolates of Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli is obvious. The extracts of Cnidium Monnieri have an antibacterial effect on Mycoplasma solani in vitro, and its minimum inhibitory concentration (MIC) value is 62.5~125μg/mL, and also can significantly reduce the pathogenicity of residual strains of Staphylococcus aureus.

 

Get in touch with us today to place your order or for any inquiries. We're here to support your journey to a healthier lifestyle! Add my WhatsApp