In vitro research

Estrogen is a moderate diuretic sodium and vasodilator in rats. The efficacy of oral administration of estrol is about 8 times lower than oral administration of furosemide.

In the isolated aortic rings pre constricted by the administration of epinephrine, the administration of estrol relaxes the constricted aorta (with a concentration of 58.9 ± 16 at 50% maximum activity) μ M) [4].

Eosin has anticancer activity and inhibits tumor formation through DMBA induced apoptosis in breast tumor rats. In addition, estrol exhibits liver protective effects by acting as an antioxidant and reducing cell apoptosis [5].