EUK-134， It is a small molecule antioxidant and anti-aging active substance with unique personality, possessing excellent antioxidant properties. 

Its birth combines the dual functions of superoxide dismutase (SOD) and catalase (CAT), effectively improving cell damage caused by oxidative stress.

EUK-134 has a small molecular weight, which is conducive to penetration and absorption on the surface of the skin. It can directly penetrate the skin and enter the interior of the skin to exert its powerful effects. It is essentially a catalyst, and its quantity does not decrease after the reaction. It can be reused with a small amount and more stable properties

In vitro research

EUK134 exhibits strong catalase and superoxide dismutase activity, which can protect human fibroblasts from cytotoxicity caused by glucose and glucose oxidase. EUK 134 (20 μ M) can prevent A β - induced proliferation of microglia in vitro. In SK-N-MC cells, by inhibiting MAPK channels to attenuate oxidative stress, EUK134 protects neuronal cells from H (2) O (2) toxicity and leads to reduced expression of pro apoptotic genes p53 and Bax, while also enhancing the expression of anti apoptotic Bcl-2 gene. EUK 134 significantly inhibits the formation of amyloid protein at two molar ratios of 1:1 and 5:1 (drug to protein).