Product

Fumagillin CAS 23110-15-8
Fumagillin CAS 23110-15-8

Fumagillin CAS 23110-15-8

Product Name: Fumagillin
Synonyms: 1-oxaspiro(2,5)oct-6-ylester;2,4,6,8-decatetraenedioicacid,mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-buteny;5beta,6beta(all-e)]]-theta;6,8-decatetraenedioicacid,4-(1,2-epoxy-1,5-dimethyl-4-hexenyl)-5-methoxy-4;amebacillin;10-[[5-Methoxy-4-[2-methyl-3-(3-methylbut-2-enyl)oxiran-2-yl]-2-oxaspiro[2.5]oct-6-yl]oxy]-10-oxo-deca-2,4,6,8-tetraenoic acid;Fumagilin DCH;[3R-[3alpha,4alpha(2RX,3RX),5beta,6beta(all-E)]]-2,4,6,8-Decatetraenedioic acid, mono[5-methoxy-4-[2-methyl-3-(3-methyl-2-butenyl)oxiranyl]-1-oxaspiro[2.5]oct-6-yl] ester
CAS: 23110-15-8
MF: C26H34O7
MW: 458.54
EINECS: 245-433-8

introduction

Fumagillin is an antibiotic isolated from the fermentation broth of Aspergillus fumigatus.


Physical and chemical properties

Yellow needle shaped crystals; Melting point 194-195 ℃; Optical rotation [α] D25-26.6 ° (c=1, ethanol); Almost insoluble in water, dilute acids, saturated hydrocarbons, soluble in organic solvents such as ethanol.


purpose

Aflatoxin has both antibiotic activity and inhibitory effects on angiogenesis, thus having therapeutic effects on tumor growth.


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