summary

Lidocaine exerts local anesthesia by reversibly blocking sodium channels and blocking the transmission of action potentials on nerve fibers. Sensory nerve fibers are blocked earlier than motor nerve fibers, so low-dose lidocaine can exert selective sensory blockade.

Lidocaine also has antiarrhythmic effects and belongs to class Ib antiarrhythmic drugs. It can reduce ventricular rate, shorten action potential time and absolute refractory period, and prolong relative refractory period.

Lidocaine takes effect quickly and has a short duration. Adding adrenaline to lidocaine can reduce the systemic absorption rate, thereby prolonging anesthesia time.