Product

Peterostilbene
Peterostilbene

Peterostilbene

Product Name Trans Pterostilbene Extract CAS 537-42-8
Latin Name Pterostilbene
Appearance white powder
Specification 99%
Source Pterostilbene
Keywords Pterostilbene,Trans Pterostilbene Extract,Trans Pterostilbene Extract 

(pronounced terro-still-bene) is a beneficial dietary compound that is found in antioxidant-rich foods like blueberries, cranberries and grapes. In both human and animal studies, it has been shown to offer protection against many neurological, cardiovascular, metabolic and hematologic disorders. For example, pterostilbene benefits include protecting against memory loss, high cholesterol, high blood pressure levels and even certain types of cancer.

As a methylated stilbene molecule, it has a similar structure to the antioxidant resveratrol. Pterostilbene and resveratrol share many of the same benefits, including fighting oxidative stress, but pterostilbene has been shown to have superior bioavailability. In other words, pterostilbene is believed to be absorbed and utilized by the body more easily than similar phytonutrients, which is one reason why it’s recently caught the attention of health researchers.

Peterostilbene

What Is Pterostilbene?

Pterostilbene is a stilbene molecule and dimethylated derivative of resveratrol, an antioxidant that helps fight free radical damage which contributes to the aging process.

It was named after the Pterocarpus plant family plants, which were the first sources of pterostilbene to be discovered. Originally the compound was isolated from the red sandalwood tree (Pterocarpus santalinus) and later sourced from Pterocarpus marsupium. 

There are more than 35 different pantropical pterocarpus plants, which are native to Asia and Western Africa. Pterocarpus plants go by several names around the world, including Paduak, Narra, Indian kino tree, Malabar kino and Vijayasar. 

What is pterostilbene good for when it comes to improving your health? A 2013 review published in the journal Oxidative Medicine and Cellular Longevity states, “The antioxidant activity of pterostilbene has been implicated in anticarcinogenesis, modulation of neurological disease, anti-inflammation, attenuation of vascular disease, and amelioration of diabetes. 

Peterostilbene

Some of the many positive effects of pterostllbene include:

  • Fighting oxidative stress, thanks to its strong antioxidant activity. This allows it to help prevent and treat various chronic diseases.
  • Helping to prevent cancer and tumor growth, especially breast and colon cancers. 
  • Protecting against neurological diseases, including memory loss and dementia.
  • Fighting inflammation, the root cause of many diseases, and boosting the immune system.
  • Protecting the heart and blood vessels.
  • Naturally fighting bacterial and fungal infections of the skin.
  • Helping to prevent diabetes, high cholesterol, high blood pressure and metabolic syndrome.

Benefits

1. Fights Oxidative Stress

There’s evidence that pterostilbene has anti-inflammatory properties, reduces oxidative stress and reduces production of reactive oxygen species, which contribute to many chronic diseases. 

 In animal studies, cells treated with pterostilbene have shown increased expression of the antioxidants catalase, total glutathione, glutathione peroxidase, glutathione reductase and superoxide dismutase. 

2. May Help Prevent Cancer

Like resveratrol, pterostilbene has been reported to have cancer-preventive activity. In several clinical trials, it has been shown to be a natural anticancer agent due to its antioxidant and antineoplastic properties (antineoplastic means it acts to prevent, inhibit or halt the development of a neoplasm, or a tumor). 

Consuming pterostilbene helps lead to improved function of normal cells and inhibition of malignant cells. Some of the ways that it inhibits cancer growth is through the alteration of cancerous cell cycles, induction of apoptosis (cell death), and inhibition of tumorigenesis and metastasis.

A number of studies have found that blueberry extract containing pterostilbene can be especially helpful for preventing and treating breast cancer.  Results from experiments using blueberry juice and extract derived from velvetleaf blueberries showed that blueberry exerts an antiproliferative effect against breast cancer cell lines due to the presence of specific chemical components that modify carcinogenic pathways. 

 There’s some evidence that pterostilbene may help inhibit cytochrome P450, an enzymes that activates a variety of compounds known as “procarcinogens” that make carcinogens more dangerous.

3. Supports Cognitive Health

Blueberries are known to be a powerful brain food because they are a great source of protective antioxidants that can help enhance cognition and protect memory.  While more studies are needed to confirm its effects, there’s some evidence that pterostilbene supplements may help reduce symptoms like brain fog, anxiety, poor memory and difficulty learning. Due to its ability to prevent oxidative stress in the brain, pterostilbene and other similar compounds may help protect against neurological problems, including Alzheimer’s disease, cerebral injury, neuronal apoptosis, reduced brain volume and brain edema (swelling). 


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